The structure of prostaglandins is based on eicosanoic acid, a twenty carbon atoms long hydrocarbon chain with a carboxyl group. The chain contains one five-membered ring made of eight to twelve carbon atoms. All prostaglandins contain at least a hydroxyl group on carbon atom 15 and a double bond at carbon atom 13.
Prostaglandins are associated with hormone-like functions. They interact with G-protein-linked receptors on the cell surface to activate cellular signal transduction pathways. Prostaglandins coordinate a multitude of physiological processes. The best-known function of prostaglandins in cells is that they modify inflammatory response. Prostaglandin synthesis is inhibited by non-steroidal anti-inflammatory drugs like aspirin to limit their pro-inflammatory effects.
Here you can read more about the analysis of prostaglandins performed at Lipotype:
#FattyAcyls #lipid #lipidomics #MassSpectrometry #prostaglandin #eicosanoid
