Home   Lipotype Lipidomics   Fatty Acyls   Fatty Acids   VLCFA 

Very Long Chain Fatty Acid

We provide MS-based lipid analysis of VLCFA fatty acyls in a variety of sample types and deliver results in six or less weeks.
Request analysis

Details

Fatty Acyls
Lipid Category
Fatty Acids
Lipid Group
Very Long Chain Fatty Acid
Lipid Class

About the structure and biological function of VLCFA

Structure. Very long chain fatty acids (VLCFA) belong to the group of fatty acids within the fatty acyls. Their structure consists of a hydrocarbon chain of twenty-two to thirty carbon atoms and a carboxylic head group. The hydrocarbon chain of VLCFAs can further contain multiple double bonds, and be branched or linear.

Function. Very long chain fatty acids occur in many plant waxes and some animal waxes. VLCFAs are predominantly found in the ceramide backbone of sphingolipids. They alter the membrane thickness and rigidity locally and contribute to the formation of lipid rafts, subdomains of the cell membrane. Both, excess and deficiency of VLCFAs in the brain has been linked to neurological disorders. VLCFA level in plasma is used to diagnose adrenoleukodystrophy.

Research articles

See all research articles

VLCFA lipidomics analysis with
Lipotype

Structural detailsmolecular species
Variants identified > 10
Approachtargeted
Methodmass spectrometry
DeviceAgilent 1290 HPLC + 6495 Triplequad
Quantificationyes
Delivery time6 weeks
Lipidomics datapmol & mol%
Figuresincluded

EXAMPLE STRUCTURE
VLCFA

An example for the molecular structure of FA 24:1;0.

Interested in
VLCFA
analysis?

Request analysis now

Lipid Navigator

Categories

Fatty Acyls Glycerolipids Phospholipids Sphingolipids Sterol Lipids Prenol Lipids

Groups

Fatty Acids Fatty Esters Fatty Amides Octadecanoids Eicosanoids Docosanoids Glycerol Esters Ester Phospholipids Ether Phospholipids Diphospha­tidyl­glycerols CDP-Glycerols Sphingoid Bases Ceramide Lipids Cerebrosides Diglycosyl­ceramides Phospho­sphingolipids Gangliosides Globosides Sulfoglyco­sphingolipids Cholesterol Lipids Ergosterol Lipids Isoprenoids Quinones

Classes

FFA BCFA SCFA MCFA LCFA VLCFA WE CAR NAE oxiOME oxiODE Pgd LT TX LX IsoP oxiETrE oxiETE oxiEPE MaR RvD PD oxiDPA oxiDHA TAG DAG MAG PA PC PE PG PI PS LPA LPC LPE LPG LPI LPS BMP PC O- PE O- LPC O- LPE O- CL CDP-DAG Sph dhSph SphP dhSphP GlcSph GalSph Cer CerP dhCer doxCer EOdS EOS EOP EOH NdS NS NP NH AdS AS AP AH HexCer GlcCer GalCer DiHexCer LacCer SM CerPE IPC MIPC M(IP)2C GM1 GM2 GM3 GM4 GD1 GD2 GD3 GT1 GT2 GT3 GQ1 Gb3 Gb4 Sulf Chol CE oxiChol Lano Desm Lath Erg EE C10T C15T Sqe oxiSqe UQ
i
Learn more about our services for
Name

ABOUT LIPOTYPE

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

★★★★★

  • Thank you once again. The timing is extremely helpful to us.

    Susan Macdonald

    Aldeyra Therapeutics

  • Thank you very much. The results look fantastic!

    Stan Neufeld

    Friedrich Miescher Institute

  • The high-speed turn around when under revision really helped us!

    Rose E Goodchild

    KU Leuven

  • We highly appreciate the personal support and consultation.

    Rainer Voegeli

    DSM Skin Biology

  • We have been quite impressed. The results clearly indicate a difference.

    Pietro De Camilli

    Yale University

  • Cooperating with Lipotype, I enjoy custom packages and great support!

    Olga Ramich

    DIfE

  • After moving from one continent to another, I still prefer Lipotype!

    Julie Jacquemyn

    University of Alberta

  • Thank you very much for my new and shiny lipidomics data set!

    Ilya Levental

    University of Virginia

  • Lipotype Lipidomics is instrumental to our studies of membranes.

    Christopher J Stefan

    University College London

  • Lipotype is truly dedicated to supporting scientists in their research.

    Anonymous

    Anonymous

Request Analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!

*